Process Development

Abzena has expertise in both upstream and downstream process development. Process development services can stand alone or can be integrated into preclinical and clinical manufacturing projects. Abzena focuses on improving yield at each stage of development by optimizing each step in the process.

Cell Line Development

Abzena offers a variety of CHO manufacturing cell line development packages to meet customers’ requirements. We can develop transfection pools for proof of concept through to high expressing clonal cell lines ready for cGMP manufacture.

Upstream Process Development

  • Cell line expansion and cell banking
  • Production scale-up from 100mL to 500L with batch and fed-batch, and up to 15,000L in perfusion
  • Specialize in developing upstream bioprocessing systems through single-use devices

Downstream Process Development

  • Optimization of harvest, clarification, concentration, viral clearance, purification (capture, polishing, nanofiltration), conjugation and formulation
  • Development and scale-up with an emphasis on closed systems employing single-use technology

Working with Abzena

Abzena’s contract development and manufacturing services are tailored to each project to ensure that the objectives are met or exceeded. Experienced project teams are assigned to each study focusing on progressing projects through to results in the minimum amount of time. Our clients widely regard us as professional and attentive partners who deliver quality results in a timely manner. To get more information, a quote or to schedule a teleconference please contact us.

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