Small Molecule Manufacturing Process | Abzena

Small Molecule Manufacture

Abzena currently has the capability of scaling multi-step procedures to produce up to 100 g quantities of material.


  • Route design and optimisation
  • Trouble-shooting
  • Process optimisation
    • Avoidance of chromatography
    • Solvent minimisation
    • Impurity profiles
    • Avoidance of potential genotoxic reagents
    • Manufacturability
  • World-wide sourcing for best quality and cost


  • Non-GMP batches for toxicology studies
  • In-house manufacturing up to 100 g
  • Full batch records for regulatory submissions
  • Tech-transfer for multi-kg GMP scale

High potency

  • Capacity of 25 -100 g for highly potent and cytotoxic small molecules
  • A five-band system of classifying risk is in place for highly potent compounds

Working with Abzena

Abzena’s chemistry development and manufacturing services are tailored to each project to ensure that the objectives are met or exceeded.

We collaborate with a wide range of organisations from virtual companies through to big pharma, including many of the world’s top companies, as well as academic research groups from across the globe.

To get more information, a quote or to schedule a teleconference please contact us.

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