Development & Manufacturing

Abzena provides an array of cGMP and non-GMP production services for recombinant proteins, antibodies, conjugates, gene therapy, vaccine and cell therapy products for preclinical and clinical materials. Our expertise in employing single-use technology allows for rapid turnaround times and the most cost effective solutions in the industry.

  • Process development and scale-up
  • Multiple expression systems and cell types: mammalian; bacterial
  • Cell banking and storage
  • Fill and finish
  • Cell line development and optimization
  • Media development and optimization
  • Purification, viral clearance
  • Conjugation
  • Analytical support
  • Spent media analysis of cell cultures
  • Plasmid DNA production and purification

Single use technology

Abzena employs single-use flexible technology throughout the production process. Our multi-product facility has been designed to take full advantage of the advances in single-use technology.

The advantages of single-use technology include:

  • Reduces risk of cross-contamination
  • Lower cost as a result of fewer system requirements
    • Single-use components are clean and ready to use when supplied, which mitigates the need for sterilization and decreases the requirement for formerly essential services such as water for irrigation systems and steam generators. The systems are less complex, minimizing engineering requirements resulting in the elimination of clean-in-place or steam-in-place operations along with the associated piping, valves, controls and pressure rating of vessels
    • Quick turn-around time between runs
    • Less complex engineering design means faster process development
    • Allows for maximum flexibility, we can rapidly scale up your process from 1L to 15,000L in perfusion at a lower overall cost than with traditional steel bioreactors

Working with Abzena

Abzena’s contract development and manufacturing services are tailored to each project to ensure that the objectives are met or exceeded. Experienced project teams are assigned to each study focusing on progressing projects through to results in the minimum amount of time. Our clients widely regard us as professional and attentive partners who deliver quality results in a timely manner. To get more information, a quote or to schedule a teleconference please contact us.

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