Abzena has many years of experience in humanizing antibodies, with numerous antibodies designed using Abzena technology currently in clinical trials. Abzena offers multiple solutions to antibody humanization suitable for every development path.
Abzena’s proprietary antibody humanization technology is used to generate humanized and fully functional antibodies devoid of T cell epitopes in the variable region sequences to reduce immunogenicity in patients. Read more >>>
Abzena offers a germline CDR graft humanization service in which the CDRs of your starting antibody are grafted onto an appropriate human antibody germline acceptor framework. Read more >>>
Our Design Only service for either Composite Human Antibody™ or Germline humanisation gives you the flexibility to carry out investigations in your own timescale. Read more >>>