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Cell Line Development
Abzena oﬀers a variety of manufacturing cell line development packages to meet customers’ requirements. We can develop transient pools through to high expressing clonal cell lines ready for cGMP manufacture.
We have developed high-expressing mammalian cell lines for the production of antibodies and other proteins, including those designed using our humanization and deimmunisation technologies. Cell lines are typically developed using Composite CHO™ (Chinese Hamster Ovary) cells but other cell lines suitable for commercial manufacture are available. All cell lines have been used to produce novel biologics and/or biosimilar products. Manufacturing cell lines can be transferred to our own GMP manufacturing facility in San Diego or directly to you, or your preferred contract manufacturing organisation (CMO).
Abzena can develop CHO, NS0 and Sp2/0 biosimilar cell lines for the production of biosimilar products. The development programmes include bespoke quality assessment tailored to individual projects and your requirements.
Abzena assesses cell line and product quality at multiple stages of the project as an integral part of the cell line development process to determine whether the product will have the required PQAs.
Working with Abzena
Our services are tailored for each project to ensure that the objectives are met or exceeded. Experienced project teams are assigned to each study focusing on progressing projects through to results in the minimum amount of time. Our clients widely regard us as professional and attentive partners who deliver quality results in a timely manner.
For more information or a quote for our cell line development services and technologies contact us.