Linker Payload

Tailored solutions, reliably delivered.

Linker payload architecture is fundamental to the successful design of your drug candidate.

Developing a safe and effective ADC drug requires the assembly of the desirable linker with the payload and the monoclonal antibody (mAb). The designed linker helps the antibody to selectively deliver and release the drug to the tumor site. Our extensive knowledge regarding mAbs, linkers, and payloads ensures a robust lead drug candidate.

Through utilization of our tailored solutions we identify and de-risk your clinical candidates for development and ensure stage-specific milestones are met.

To accelerate lead drug candidate selection, we apply our knowledge in linker payload design and synthesis, high potency materials, and analytical method development to develop your complex ADCs.

Linker Payload Design and Synthesis

Supporting your candidate ranking and lead selection process, we determine the optimal design of linker payload architecture and profiling in a series of in silico, in vitro and ex vivo activity and safety assessments.

We use a matrix evaluation and developability approach to streamline and de-risk the development, scale, and manufacture of your linker payloads.

Analytical Method Development

Ensuring the quality of your product and processes, we have extensive capabilities to identify, develop and deliver a comprehensive set of characterization, screening, release, and stability-indicating assays.

Streamlining your project and assuring scalability, our experienced R&D and analytical teams collaborate closely to ensure that the process developed for the manufacturing of your products meets your desired quality attributes.

Highly Potent Material

Utilizing a combination of technology, infrastructure, and expertise, we provide you with seamless, flexible highly potent API development and manufacturing tailored to your specific needs.

Our purpose-built facilities have primary engineering controls for safety and are managed by expert teams to phase-appropriately develop, scale, and manufacture your highly potent API with reduced timelines, complexity, and risk.

Let’s move medicine forward

The asset you’re developing right now can make a real difference for human health. Let us apply our wealth of experience to accelerate and maximize its potential.