Antibody Drug Conjugate Manufacturing – Abzena

Antibody Drug Conjugate Manufacturing

  • Up to 15,000L scale GMP mammalian manufacturing using single use technology
  • Extensive experience in non-GMP/GMP chemical manufacturing for ADC’s, payloads and payload-linkers
  • Continually expanding service aiming for full GMP ADC manufacture

Full Manufacturing Support

Moving out of the drug discovery phase and into clinical development requires an increase in the required quantity and quality (cGMP) of your ADC. Abzena’s ADC manufacturing allows you to continue with Abzena for cGMP manufacture of your ADC through clinical trials.

Mammalian Manufacturing

Abzena provides cGMP production and purification for recombinant proteins and antibodies for use in preclinical and phase I and II clinical trials. Abzena has extensive experience in the use of single-use technology which provides flexibility in the production process. The services provided include expression from 1L to 1,000L in batch or fed batch mode and up to 15,000L in perfusion mode through to final fill/finish of Drug Product up to 2000 vial configuration.

Chemical Manufacturing

Abzena’s chemical manufacturing plant in Bristol, PA provides route design and optimisation through to cGMP scale for payloads, cytotoxics and payload linkers depending on HPAPI status.

Antibody Drug Conjugate Manufacturing

Abzena can provide non-GMP manufacturing of full ADCs up to 10g for toxicology studies and is continually investing in and expanding its manufacturing services and aims to offer full cGMP manufacturing for ADCs by Q4 2017. For full information on our mammalian and chemical manufacturing capabilities please see our manufacturing pages here.

shutterstock_143646112Working with Abzena

Abzena’s services are tailored for each project to ensure that the objectives are met or exceeded. Experienced project teams are assigned to each study focusing on progressing projects through to results in the minimum amount of time. Our clients widely regard us as professional and attentive partners who deliver quality results.

To get more information, a quote or to schedule a teleconference please contact us.

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