Antibody Drug Conjugation | ADC Company | Abzena

Antibody Drug Conjugation at Abzena

One solution doesn’t fit all

At Abzena we understand that there is no one solution for the development of antibody drug conjugates and that every target brings its own set of challenges to development. Abzena can help guide your development of a matrix that can be tested to find the ideal ADC for your patients.

  • Benefit from access to Abzena’s wide range of expertise and technology to streamline your ADC development program
  • Complete target to manufacturing service offering for all ADC components including final conjugation
  • Generate a matrix of candidates for ex-vivo assessment before commiting to further development

1ADC Development

Abzena’s services are customised to accelerate the selection of the optimal ADC candidate for your target of interest. Different conjugations technologies can be assessed side by side for efficacy allowing the ability to screen and rank multiple product canidates to optimise your investment right from the begining. Read more >>>

1Conjugation Technologies

At Abzena we understand that there is no one solution to the development of antibody drug conjugates and that every target brings its own set of challenges to development. Abzena can help guide your building of a matrix that can be tested to find the ideal ADC for your patients. Read more >>>

1Payloads

There are many varieties of payloads available for the development of anti body drug conjugates, each has its own toxicity and profile for use in different tumours and with different targetting moeties. Abzena can synthesise chemical paylaods at its Bristol, USA, plant or help develop protein and DNA conjugates at its Cambridge site.  Read more >>>

1Analysis and Characterisation

Abzena’s state of the art labs are equipped with an array of analytical and preparative HPLC in instruments and columns allowing the most difficult seperations. This, in conjunction with LC/MS and MALDI-ToF mass spectometers and 500-MHz and 300-Mhz NMR spectrometers, gives the capability to offer clients valuable and reliable analytical services.  Read more >>>

1Manufacturing

Abzena San Digo and Bristol sites offer large manufacturing capabilities for antibody drug conjugates at multiple scales including non-GMP and GMP manufacturing.  Read more >>>

 

Antibody and Protein Engineering

Abzena and OBI Pharma sign ThioBridge™ licence agreement

Cell Line Development

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