Fc Binding & Function Assays
Furthermore, some toxicities observed in vivo have been linked to binding of ADCs to healthy cells via their Fc domain. Consequently, assessment of binding to Fc receptor and Fc-mediated functions such as ADCC, CDC and ADCP constitute an increasingly relevant safety consideration when developing an ADC.
Working with Abzena
Abzena’s undertakes bioassays on behalf of clients as standalone projects or as part of larger development projects. We focus on developing the correct bioassay to help you understand your molecule and will help guide you in the correct.
To get more information, a quote or to schedule a teleconference please contact us.