Small Molecule Manufacture

Abzena currently has the capability of scaling multi-step procedures to produce up to 100 g quantities of material.

Scale-up

  • Route design and optimization
  • Trouble-shooting
  • Process optimization
    • Avoidance of chromatography
    • Solvent minimization
    • Impurity profiles
    • Avoidance of potential genotoxic reagents
    • Manufacturability
  • World-wide sourcing for best quality and cost

Manufacturing

  • Non-GMP batches for toxicology studies
  • In-house manufacturing up to 100 g
  • Full batch records for regulatory submissions
  • Tech-transfer for multi-kg GMP scale

High potency

  • Capacity of 25 -100 g for highly potent and cytotoxic small molecules
  • A five-band system of classifying risk is in place for highly potent compounds

Working with Abzena

Our services are tailored for each project to ensure that the objectives are met or exceeded. Experienced project teams are assigned to each study focusing on progressing projects through to results in the minimum amount of time. Our clients widely regard us as professional and attentive partners who deliver quality results in a timely manner.

For more information or a quote for our bioconjugation and chemistry services and technologies contact us.

Interested in our services? Get In Touch